American Pickers is een Amerikaanse realityserie van de zender History. De serie ging in première op 18 januari 2010.
American Pickers volgt twee van de meest ervaren ‘pickers’: Mike Wolfe, eigenaar van Antique Archaeology, en zijn zakenpartner Frank Fritz. Zij zijn op jacht naar voorwerpen met historische waarde, verzamelwaarde en voorwerpen uit de popcultuur die al lang vergeten zijn door hun eigenaren. Ze ontmoeten gaandeweg mensen wier verhalen ons meer vertellen over Amerikaanse levens en de geschiedenis.
Concerned about slow sales and high expenses, Danielle tells the guys they need to step up their game and make some serious money. Mike and Frank feel the pressure. They uncover lots of great stuff in Tony’s sprawling Illinois collection, but not the big-ticket item they’re looking for. It doesn’t get much better in a small town they come across. There, they spot some great vintage garage signs, and although they’re not for sale, Ken has room after room of unusual items, including an early bicycle and rare Victorian-era erotica. But their luck really changes when Danielle calls with a lead about Hobo Jack. When the guys walk into his hidden, heavily wooded overgrown property, they are surprised by his incredible collection. But will they find the mother lode they’ve been looking for?